Louisville Football Dominates Season Opener Against EKU

August 30, 2025

The University of Louisville Cardinals kicked off their 2025 football season with a strong home performance at L&N Federal Credit Union Stadium, defeating their in-state FCS rivals, the Eastern Kentucky Colonels, by a commanding score of 51-17.

Game Highlights & Standout Performers

  • Isaac Brown was electric on the ground, rushing for 126 yards and scoring two touchdowns  .
  • Louisville quarterback Miller Moss posted a solid outing, completing 17-of-25 passes for 223 yards, tossing one touchdown, but also threw two interceptions.
  • Eastern Kentucky cornerback Vito Tisdale Jr. made his presence felt, grabbing two interceptions—one returned for a score—highlighting EKU’s moments of resistance.
  • Special teams had their shine—Caullin Lacy electrified the crowd with a 93-yard punt return, the second-longest in school history.
  • Defensive pressure was notable as well, led by Clev Lubin and supported by a vibrant home crowd of 50,536 fans.

Game Flow & Key Stats

Louisville racked up 542 total yards compared to EKU’s 150, asserting their dominance in both phases of the game. The Cardinals grabbed a 21-7 lead in the first half and pushed ahead to 41-7 at the break—crushing any hopes of a comeback.

Historical Context & Season Outlook

  • Louisville entered the matchup as a heavy 38.5-point favorite and historically dominated EKU with a 20-8-1 series record.
  • Today’s outcome continues Louisville’s trend of lopsided season openers against FCS opponents, building on a recent history of decisive victories.
  • Their performance looks to boost them into the AP Top 25, especially with losses by teams previously ranked close to the Cardinals.

Looking Ahead….

Louisville improves to 1-0, while EKU falls to 0-1. Next up: Louisville hosts James Madison on Friday, Sept. 5, 2025.

Photos by: Roscelle Griffin