August 30, 2025
The University of Louisville Cardinals kicked off their 2025 football season with a strong home performance at L&N Federal Credit Union Stadium, defeating their in-state FCS rivals, the Eastern Kentucky Colonels, by a commanding score of 51-17.
Game Highlights & Standout Performers
- Isaac Brown was electric on the ground, rushing for 126 yards and scoring two touchdowns .
- Louisville quarterback Miller Moss posted a solid outing, completing 17-of-25 passes for 223 yards, tossing one touchdown, but also threw two interceptions.
- Eastern Kentucky cornerback Vito Tisdale Jr. made his presence felt, grabbing two interceptions—one returned for a score—highlighting EKU’s moments of resistance.
- Special teams had their shine—Caullin Lacy electrified the crowd with a 93-yard punt return, the second-longest in school history.
- Defensive pressure was notable as well, led by Clev Lubin and supported by a vibrant home crowd of 50,536 fans.
Game Flow & Key Stats
Louisville racked up 542 total yards compared to EKU’s 150, asserting their dominance in both phases of the game. The Cardinals grabbed a 21-7 lead in the first half and pushed ahead to 41-7 at the break—crushing any hopes of a comeback.
Historical Context & Season Outlook
- Louisville entered the matchup as a heavy 38.5-point favorite and historically dominated EKU with a 20-8-1 series record.
- Today’s outcome continues Louisville’s trend of lopsided season openers against FCS opponents, building on a recent history of decisive victories.
- Their performance looks to boost them into the AP Top 25, especially with losses by teams previously ranked close to the Cardinals.
Looking Ahead….
Louisville improves to 1-0, while EKU falls to 0-1. Next up: Louisville hosts James Madison on Friday, Sept. 5, 2025.
Photos by: Roscelle Griffin

Roscelle Griffin, a talented photographer from Johnson City, Tennessee, excelled as a women’s basketball player at the University of Louisville. Her passion for photography, ignited by her grandmother’s gift of a Polaroid camera, now drives her to capture moments that transport viewers into a world of boldness and excitement. Roscelle’s media company, 502 Media Now, specializes in sports videography and photography, showcasing the dynamic world of sports while also excelling in real estate, headshots, weddings, and events.